LucentMed is a manufacturer and supplier of liquid-based cytology brushes. We operate cleanrooms built to international GMP standards and hold ISO 13485, ISO 9001, and CE certifications. Our products meet medical standards and are suitable for various mainstream gynecological screening procedures, including Pap smears, TCT (ThinPrep Cytology Test) liquid-based cytology, and HPV genotyping.
The Liquid-based Cytology Brush, manufactured by the specialized medical product company LucentMed, features a curved brush head and a three-dimensional structure with multiple rows of bristles; this design enables the collection of an ample cellular sample, thereby enhancing the sensitivity and negative predictive value for the detection of early-stage lesions.
What is a Liquid-Based Cytology Brush?
The liquid-based cytology brush is a disposable medical device designed to collect cell samples from the cervix and endocervical canal, primarily for use with liquid-based cytology testing.
Featuring soft, flexible bristles, the brush enables the uniform collection of exfoliated cells from both the cervical surface and the endocervical canal. The brush head is subsequently placed into a preservation solution for processing, ensuring high-quality samples for downstream cytological analysis.
Compared to traditional smear sampling methods, this specialized brush enhances the integrity of cell collection and the quality of sample preservation, making it suitable for applications such as gynecological check-ups, cervical cancer screening, the diagnosis of gynecological conditions, and clinical laboratory testing.
Key Components
1. Soft Sampling Brush Head
The brush head features soft, flexible nylon bristles that ensure thorough contact with the external cervical os and the endocervical canal. This design facilitates the collection of a higher yield of viable cells while minimizing tissue irritation and enhancing patient comfort.
2. Medical-Grade Handle
The handle is constructed from medical-grade plastic, offering excellent strength and a secure grip, allowing healthcare professionals to precisely control the sampling process.
3. Detachable Brush Head (Optional)
The brush supports a customizable snap-off design; upon completion of sampling, the brush head can be placed directly into the preservation solution. This minimizes cell loss during sample transfer and improves testing efficiency.
Product Specifications
Parameter Category
Wire Type
Primary Material
Bristles: Nylon filaments wound with stainless steel wire
Tip bead: Epoxy resin (on select models)
Common Specifications
A1, A2, A3, A4, etc.
Brush Head Design
Broom-like or spiral shape; utilizes wire elasticity to conform to the shape of the cervix
Total Length
Typically 140mm – 170mm, depending on handle design
Sterilization Method
Ethylene oxide (EO) sterilization
Residual Limit Standard
Residual ethylene oxide ≤ 10µg/g
Scope of Application
Intended for endocervical cell collection and vaginal secretion sampling; certain designs facilitate deeper access into the cervical canal
Liquid-based Cytology Brush vs. Traditional Cervical Scraper: What Is the Difference?
Comparison Criteria
Liquid-based Cytology Brush
Traditional Cervical Spatula
Sampling Method
Soft bristles rotate to collect cervical cells
Collects samples by gently scraping the cervical surface
Sampling Range
Covers both the external cervical os and the endocervical canal (transformation zone)
Primarily collects cells from the surface of the external cervical os
Cell Collection Efficiency
Ensures more uniform and comprehensive cell collection
Highly dependent on operator technique
Sample Processing Method
Brush head is processed in liquid-based preservation solution
Cells are smeared directly onto a glass slide
Sample Preservation Quality
Preservation solution minimizes cell loss and contamination
Prone to cell loss or uneven distribution during transfer
Clinical Application
Liquid-Based Cytology (LBC) testing
Conventional Pap Smear
Patient Comfort
Soft bristle design causes minimal irritation
Spatula is relatively rigid; patient comfort is comparatively lower
Single-use
Yes
Yes
Suitable Facilities
Hospitals, gynecology clinics, health check-up centers, laboratories
Hospitals and primary healthcare facilities
Product Packaging
LucentMed offers a range of standard packaging options as well as OEM/ODM custom packaging solutions tailored to clients' sales channels, brand positioning, and shipping requirements.
1. Individual Sterile Packaging
Our standard packaging method features each Liquid-based Cytology Brush in individual sterile packaging (EO sterilized). This meets the procurement needs of medical institutions, minimizes the risk of cross-contamination, and allows healthcare professionals to use the product immediately.
2. Outer Carton Packaging
We use high-strength, export-grade corrugated cardboard cartons that are moisture- and crush-resistant. We support specific packing quantities and offer customization for shipping marks and carton labeling.
3. Custom Packaging Services
In addition to standard options, LucentMed provides one-stop custom packaging services based on client needs, including:
Packaging formats: Individual packaging, combination packs, kit packaging, etc.
Branding: Logo printing, private labeling, and custom brand packaging.
Packaging design: Color boxes, instruction manuals, hang tags, and label design.
Multilingual support: Packaging available in English or multiple languages to suit target markets.
Export packaging optimization: Designed to meet the requirements of sea, air, and cross-border logistics.
FAQ
Q1: What is the primary use of the Liquid-based Cytology Brush?
A: The Liquid-based Cytology Brush is specifically designed to collect exfoliated cervical cells and is suitable for early cervical cancer screening.
Q2: Why does the brush head feature a broom-like anatomical design?
A: Cervical precancerous lesions commonly occur in the squamocolumnar junction—an irregularly shaped area situated between the external cervical os and the endocervical canal.
The broom-like brush head design allows it to conform to both the external cervical os and the inner wall of the endocervical canal with a single rotation.
Q3: How many cells can be collected in a single sampling?
A: A single rotation of the LucentMed disposable sterile cervical brush collects over 1.4 million exfoliated cervical cells, far exceeding the minimum cell count required for liquid-based cytology testing (typically 50,000–100,000).
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